Calum Chambers scored and was booked as he played the entirety of Fulham’s 2-1 defeat to Chelsea.
Takuma Asano played the whole game as Hannover lost 5-1 to Stuttgart.
Emiliano Martinez played the full game as Reading beat Ipswich Town 2-1.
David Ospina was brought on in the 27th minute as Napoli lost 2-1 to Juventus.
Krystian Bielik played the majority of the game before being substituted in the closing moments as Charlton Athletic drew 1-1 with Doncaster Rovers.
Matt Macey was brought on in the 80th minute as Plymouth Argyle lost 2-0 to Sunderland.
Reiss Nelson was brought on in the 78th minute as Hoffenheim lost 3-2 to Eintracht Frankfurt.
Kelechi Nwakali wasn’t involved as Porto B drew 1-1 with Famalicao.
Emile Smith Rowe wasn’t fit enough to feature as RB Leipzig won 1-0 against Nuremberg.