Lucas Perez played the full game up front and scored his first goal of his latest spell at Deportivo La Coruna in the 2-1 victory against Getafe, for whom Emiliano Martinez was an un-used substitute.
Kelechi Nwakali started and played 61 minutes as VVV-Venlo beat Excelsior 2-0.
Stephy Mavididi was brought on in the 77th minute as Preston North End drew 2-2 with Sunderland.
Takuma Asano was an un-used substitute as Stuttgart lost 2-1 to Eintracht Frankfurt.
Marc Bola was an un-used substitute as Bristol Rovers beat Plymouth Argyle 2-1.
Joel Campbell wasn’t involved as Real Betis drew 4-4 with Real Sociedad.
Cohen Bramall wasn’t involved and Carl Jenkinson missed out through injury as Birmingham City lost 6-1 to Hull City.