Calum Chambers played the full game at right-back and provided an assist as Middlesbrough lost 3-1 to West Ham United.
Jack Wilshere played the whole game as Bournemouth drew 2-2 with Watford.
Wojciech Szczesny played 90 minutes and kept a clean sheet as Roma beat Cagliari 1-0.
Jon Toral made his Rangers debut as he played 63 minutes in the 2-1 Scottish Cup win over Motherwell.
Dan Crowley made his first start for Go Ahead Eagles and played 89 minutes in the 1-1 draw with Excelsior.
Kelechi Nwakali played the entirety of MVV Maastricht’s 2-1 loss against VVV Venlo. Stefan O’Connor was an unused substitute.
Joel Campbell came on as a substitute in the 63rd minute as Sporting Lisbon drew 2-2 with Maritimo.
Tafari Moore played the whole game as Utrecht II lost 3-0 to Dordrecht.
Julio Pleguezuelo was introduced as an 88th minute substitute as Mallorca drew 1-1 with Reus Deportiu.
Takuma Asano‘s Stuttgart weren’t in action this weekend.